Article
Increased base change mutations at G:C pairs in Escherichia coli deficient in endonuclease III and VIII.
Journal of radiation research - 1 Dec 2001
Tano K, Iwamatsu Y, Yasuhira S, Utsumi H, Takimoto K
Abstract excerpt
Various types of mutation induced by oxidative DNA damage, induced by hydrogen peroxide and riboflavin photosensitization, were determined in Escherichia coli (E. coli) mutants deficient in endonuclease III (endo III) and endonuclease VIII (endo VIII). The majority of hydrogen peroxide-induced and spontaneous mutations consisted of G:C to A:T and to T:A base changes, shown on the mutation assay system by a...
Topics
- Base Sequence
- Deoxyribonuclease (Pyrimidine Dimer)
- Endodeoxyribonucleases
- Escherichia coli
- Escherichia coli Proteins
- Genes, Suppressor
- Mutation
- RNA, Transfer