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Article

Specificity of mutations induced by riboflavin mediated photosensitization in the supF gene of Escherichia coli.

Mutation research - 3 Dec 1998

Tano K, Akasaka S, Hashimoto M, Asano M, Yamamoto K, Utsumi H, Takimoto K

Abstract excerpt

Riboflavin-mediated photosensitization has been shown to produce 8-hydroxyguanine (oh8Gua) in DNA. We investigated the specificity of mutation of photosensitized supF gene induced in Escherichia coli. The oh8Gua repair deficient E. coli mutant mutM and mutY were transformed with plasmid pUB3 carrying the supF gene irradiated with white light in the presence of riboflavin. Under these conditions, riboflavin...

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Identifiers

PMID: 9838023
DOI: 10.1016/s1383-5718(98)00137-5

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Specificity of mutations induced by riboflavin mediated photosensitization in the supF gene of Escherichia coli.PMID 9838023Read ↗

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