Article
Specificity of mutations induced by riboflavin mediated photosensitization in the supF gene of Escherichia coli.
Mutation research - 3 Dec 1998
Tano K, Akasaka S, Hashimoto M, Asano M, Yamamoto K, Utsumi H, Takimoto K
Abstract excerpt
Riboflavin-mediated photosensitization has been shown to produce 8-hydroxyguanine (oh8Gua) in DNA. We investigated the specificity of mutation of photosensitized supF gene induced in Escherichia coli. The oh8Gua repair deficient E. coli mutant mutM and mutY were transformed with plasmid pUB3 carr...
Topics
- Base Sequence
- Chromatography, High Pressure Liquid
- DNA Glycosylases
- DNA, Bacterial
- DNA-Formamidopyrimidine Glycosylase
- Electrophoresis, Polyacrylamide Gel
- Escherichia coli
- Escherichia coli Proteins
- Genes, Suppressor
- Guanine
- Light
- Molecular Sequence Data
- Mutation
- N-Glycosyl Hydrolases
- Photosensitizing Agents
- Plasmids
- RNA, Transfer
- Riboflavin