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Article

Yeast polypeptide fusion surface display levels predict thermal stability and soluble secretion efficiency.

Journal of molecular biology - 8 Oct 1999

Shusta E V, Kieke M C, Parke E, Kranz D M, Wittrup K D

Abstract excerpt

Efficiency of yeast cell surface display can serve as a proxy screening variable for enhanced thermal stability and soluble secretion efficiency of mutant proteins. Several single-chain T cell receptor (scTCR) single-site mutants that enable yeast surface display, along with their double and triple mutant combinations, were analyzed for soluble secretion from the yeast Saccharomyces cerevisiae. While secretion of...

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Identifiers

PMID: 10512694
DOI: 10.1006/jmbi.1999.3130

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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