Article

Prediction of residue-specific contributions to binding and thermal stability using yeast surface display

2021-06-01

Abstract excerpt

Accurate prediction of residue burial as well as quantitative prediction of residue-specific contributions to protein stability and activity is challenging, especially in the absence of experimental structural information. This is important for prediction and understanding of disease causing mutations, and for protein stabilization and design. Using yeast surface display of a saturation mutagenesis library of the...

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Literature Corpus work: 820af2e9-1318-5c8b-890e-44fb211a6a29
DOI: 10.1101/2021.05.31.446445

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