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Article

Aspergillus nidulans mutants defective in stc gene cluster regulation.

Genetics - 1 Oct 1999

Butchko R A, Adams T H, Keller N P

Abstract excerpt

The genes involved in the biosynthesis of sterigmatocystin (ST), a toxic secondary metabolite produced by Aspergillus nidulans and an aflatoxin (AF) precursor in other Aspergillus spp., are clustered on chromosome IV of A. nidulans. The sterigmatocystin gene cluster (stc gene cluster) is regulated by the pathway-specific transcription factor aflR. The function of aflR appears to be conserved between ST- and...

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Identifiers

PMID: 10511551
DOI: 10.1093/genetics/153.2.715
PMCID: PMC1460771

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