Article
Generation of aflR disruption mutants of Aspergillus parasiticus.
Applied microbiology and biotechnology - 1 Jun 2000
Cary J W, Ehrlich K C, Wright M, Chang P K, Bhatnagar D
Abstract excerpt
The aflR gene of Aspergillus parasiticus and A. flavus encodes a binuclear zinc-finger, DNA-binding protein, AflR, responsible for activating the transcription of all known aflatoxin biosynthetic genes including itself. Studies to determine how environmental and nutritional factors affect aflR expression and hence aflatoxin production in A. parasiticus have been difficult to perform due to the lack of aflR...
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