Article
cpsA regulates mycotoxin production, morphogenesis and cell wall biosynthesis in the fungus Aspergillus nidulans.
Molecular microbiology - 1 Jul 2017
Feng Xuehuan, Ramamoorthy Vellaisamy, Pandit Sandesh S, Prieto Alicia, Espeso Eduardo A, Calvo Ana M
Abstract excerpt
The model fungus Aspergillus nidulans synthesizes numerous secondary metabolites, including sterigmatocystin (ST). The production of this toxin is positively controlled by the global regulator veA. In the absence of veA (ΔveA), ST biosynthesis is blocked. Previously, we performed random mutagenesis in a ΔveA strain and identified revertant mutants able to synthesize ST, among them RM1. Complementation of RM1 with...
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