Suppressor Mutagenesis Identifies a Velvet Complex Remediator of Aspergillus nidulans Secondary Metabolism

Abstract excerpt

Fungal secondary metabolites (SM) are bioactive compounds that are important in fungal ecology and, moreover, both harmful and useful in human endeavors (e.g., as toxins and pharmaceuticals). Recently a nuclear heterocomplex termed the Velvet complex, characterized in the model ascomycete Aspergillus nidulans, was found to be critical for SM production. Deletion of two members of the Velvet complex, laeA and veA,...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Fungal and yeast genetics research
• Share to Microbial Metabolic Engineering and Bioproduction
• Share to Microbial Natural Products and Biosynthesis