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Article

Aspergillus sporulation and mycotoxin production both require inactivation of the FadA G alpha protein-dependent signaling pathway.

The EMBO journal - 15 Aug 1997

Hicks J K, Yu J H, Keller N P, Adams T H

Abstract excerpt

The filamentous fungus Aspergillus nidulans contains a cluster of 25 genes that encode enzymes required to synthesize a toxic and carcinogenic secondary metabolite called sterigmatocystin (ST), a precursor of the better known fungal toxin aflatoxin (AF). One ST Cluster (stc) gene, aflR, functions as a pathway-specific transcriptional regulator for activation of other genes in the ST pathway. However, the...

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Identifiers

PMID: 9305634
DOI: 10.1093/emboj/16.16.4916
PMCID: PMC1170127

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Aspergillus sporulation and mycotoxin production both require inactivation of the FadA G alpha protein-dependent signaling pathway.PMID 9305634Read ↗

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