Article
Aspergillus sporulation and mycotoxin production both require inactivation of the FadA G alpha protein-dependent signaling pathway.
The EMBO journal - 15 Aug 1997
Hicks J K, Yu J H, Keller N P, Adams T H
Abstract excerpt
The filamentous fungus Aspergillus nidulans contains a cluster of 25 genes that encode enzymes required to synthesize a toxic and carcinogenic secondary metabolite called sterigmatocystin (ST), a precursor of the better known fungal toxin aflatoxin (AF). One ST Cluster (stc) gene, aflR, functions...
Topics
- Aflatoxins
- Aspergillus
- Aspergillus nidulans
- Chromatography, Thin Layer
- Fungal Proteins
- GTP-Binding Proteins
- GTPase-Activating Proteins
- Gene Expression Regulation, Fungal
- Genes, Fungal
- Mutation
- Proteins
- RNA, Messenger
- Signal Transduction
- Spores, Fungal
- Sterigmatocystin
- Transcription, Genetic