Article
Revitalization of a Forward Genetic Screen Identifies Three New Regulators of Fungal Secondary Metabolism in the Genus Aspergillus.
mBio - 5 Sept 2017
Pfannenstiel Brandon T, Zhao Xixi, Wortman Jennifer, Wiemann Philipp, Throckmorton Kurt, Spraker Joseph E, Soukup Alexandra A, Luo Xingyu, Lindner Daniel L, Lim Fang Yun, Knox Benjamin P, Haas Brian, Fischer Gregory J, Choera Tsokyi, Butchko Robert A E, Bok Jin-Woo, Affeldt Katharyn J, Keller Nancy P, Palmer Jonathan M
Abstract excerpt
The study of aflatoxin in Aspergillus spp. has garnered the attention of many researchers due to aflatoxin's carcinogenic properties and frequency as a food and feed contaminant. Significant progress has been made by utilizing the model organism Aspergillus nidulans to characterize the regulation of sterigmatocystin (ST), the penultimate precursor of aflatoxin. A previous forward genetic screen identified 23...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.