Article
Deletion of the celA gene in Aspergillus nidulans triggers overexpression of secondary metabolite biosynthetic genes.
Scientific reports - 20 Jul 2017
Guerriero Gea, Silvestrini Lucia, Legay Sylvain, Maixner Frank, Sulyok Michael, Hausman Jean-Francois, Strauss Joseph
Abstract excerpt
Although much progress has been made in the study of cell wall biosynthetic genes in the model filamentous fungus Aspergillus nidulans, there are still targets awaiting characterization. An example is the gene celA (ANIA_08444) encoding a putative mixed linkage glucan synthase. To characterize the role of celA, we deleted it in A. nidulans, analyzed the phenotype of the mycelium and performed RNA-Seq. The strain...
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