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Article

Detection of loss of heterozygosity at RAD51, RAD52, RAD54 and BRCA1 and BRCA2 loci in breast cancer: pathological correlations.

British journal of cancer - 1 Oct 1999

Gonzalez R, Silva J M, Dominguez G, Garcia J M, Martinez G, Vargas J, Provencio M, España P, Bonilla F

Abstract excerpt

Loss of heterozygosity (LOH) in loci of the 15q15.1, 12p13, 1p32, 17q21 and 13q12-13 regions may collaborate in the inactivation of RAD51, RAD52, RAD54, BRCA1, BRCA2 and possibly other genes implicated in the repair of double-stranded DNA and in DNA recombination. We investigate allelic losses in microsatellites of the RAD51, RAD52, RAD54, BRCA1 and BRCA2 regions, and their correlations with nine pathologic...

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Source

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Identifiers

PMID: 10507777
DOI: 10.1038/sj.bjc.6690722
PMCID: PMC2362917

Genes

BRCA1
BRCA2
RAD51
RAD52

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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