Article
Association between a delta opioid receptor gene polymorphism and heroin dependence in man.
Neuroreport - 28 Jul 1997
Mayer P, Rochlitz H, Rauch E, Rommelspacher H, Hasse H E, Schmidt S, Höllt V
Abstract excerpt
Two allelic variants of the delta opioid receptor gene, distinguished by a single base exchange T to C in codon 307 of the translated region, were detected in humans. The amino acid sequence was thereby not changed. The resulting C and T alleles combined to give the three genotypes CC, CT and TT. Allele C was more frequent in a sample of 103 German Caucasian heroin addicts (53.4%) than in a control group (39.1%,...
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