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Article

Inhibition of rat mammary tumorigenesis by human chorionic gonadotropin associated with increased expression of inhibin

1 Sept 1999

Abstract excerpt

This work was designed to test whether the suppression of 7,12-dimethylbenz[a]anthracene (DMBA)-induced rat mammary carcinomas by human chorionic gonadotropin (hCG) is associated with the synthesis of inhibin. For this purpose, virgin rats received 8 mg DMBA/100 g body weight; 20 d later they were injected daily with 100 IU of hCG for 40 d (DMBA+hCG group). Age-matched untreated (control), hCG-, and...

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Identifiers

PMID: 10487517
DOI: 10.1002/(sici)1098-2744(199909)26:1<10::aid-mc2>3.0.co;2-s

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Research trail→

Click a neighbor to travelStep 1 · 12 closest

Inhibition of rat mammary tumorigenesis by human chorionic gonadotropin associated with increased expression of inhibinPMID 10487517Read ↗

Hormonal approach to breast cancer preventionSemantic proximity Read ↗

Luteinizing hormone promotes gonadal tumorigenesis in inhibin-deficient mice.Semantic proximity Read ↗

Genetic Removal of Smad3 from Inhibin-Null Mice Attenuates Tumor Progression by Uncoupling Extracellular Mitogenic Signals from the Cell Cycle MachinerySemantic proximity Read ↗

Inhibin Is an Antagonist of Bone Morphogenetic Protein SignalingSemantic proximity Read ↗

Role of androgens in testicular tumor development in inhibin-deficient mice.Semantic proximity Read ↗

Antiprogestins inhibit growth and stimulate differentiation in the normal mammary gland.Semantic proximity Read ↗

Inhibin-A Antagonizes TGFβ2 Signaling by Down-Regulating Cell Surface Expression of the TGFβ Coreceptor BetaglycanSemantic proximity Read ↗

Activin induces x-zone apoptosis that inhibits luteinizing hormone-dependent adrenocortical tumor formation in inhibin-deficient mice.Semantic proximity Read ↗

Activin A Augments GnRH-Mediated Transcriptional Activation of the Mouse GnRH Receptor GeneSemantic proximity Read ↗

Activin over-expression in the testis of mice lacking the inhibin α-subunit gene is associated with androgen deficiency and regression of the male reproductive tract.Semantic proximity Read ↗

Transfection of Antisense Chorionic Gonadotropin β Gene into Choriocarcinoma Cells Suppresses the Cell Proliferation and Induces ApoptosisSemantic proximity Read ↗

[Inhibin and ovarian cancer].Semantic proximity Read ↗

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