Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Inhibin Is an Antagonist of Bone Morphogenetic Protein Signaling

28 Feb 2003

Abstract excerpt

Inhibins are endogenous antagonists of activin signaling, long recognized as important regulators of gonadal function and pituitary FSH release. Inhibin, in concert with its co-receptor, betaglycan, can compete with activin for binding to type II activin receptors and, thus, prevent activin signaling. Because bone morphogenetic proteins (BMPs) also utilize type II activin receptors, we hypothesized that BMP...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Bone Metabolism and Diseases
Share to Parathyroid Disorders and Treatments
Share to TGF-β signaling in diseases

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 12493742
DOI: 10.1074/jbc.m209710200

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Inhibin Is an Antagonist of Bone Morphogenetic Protein SignalingPMID 12493742Read ↗

Betaglycan (TGFBR3) Functions as an Inhibin A, but Not Inhibin B, Coreceptor in Pituitary Gonadotrope Cells in MiceSemantic proximity Read ↗

Endogenous Betaglycan Is Essential for High-Potency Inhibin Antagonism in GonadotropesSemantic proximity Read ↗

Identification of distinct inhibin and transforming growth factor beta-binding sites on betaglycan: functional separation of betaglycan co-receptor actions.Semantic proximity Read ↗

Normal reproductive function in InhBP/p120-deficient mice.Semantic proximity Read ↗

Inhibin-A Antagonizes TGFβ2 Signaling by Down-Regulating Cell Surface Expression of the TGFβ Coreceptor BetaglycanSemantic proximity Read ↗

Inhibin α-subunit N terminus interacts with activin type IB receptor to disrupt activin signaling.Semantic proximity Read ↗

Activins, Myostatin and Related TGF-β Family Members as Novel Therapeutic Targets for Endocrine, Metabolic and Immune DisordersSemantic proximity Read ↗

TGFBR3L is an inhibin B co-receptor that regulates female fertilitySemantic proximity Read ↗

Structural basis for a functional antagonist in the transforming growth factor beta superfamily.Semantic proximity Read ↗

Engagement of Bone Morphogenetic Protein Type IB Receptor and Smad1 Signaling by Anti-Müllerian Hormone and Its Type II ReceptorSemantic proximity Read ↗

Activin signaling as an emerging target for therapeutic interventionsSemantic proximity Read ↗

The role of bone morphogenetic proteins in ovarian function.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.