Article
Four new colon cancer susceptibility loci, Scc6 to Scc9 in the mouse.
Cancer research - 1 Sept 1999
van Wezel T, Ruivenkamp C A, Stassen A P, Moen C J, Demant P
Abstract excerpt
Germ-line mutations in APC and mismatch repair genes explain only a small percentage of all colorectal cancer cases. We have used the recombinant congenic strain mouse model to find new loci that are involved in the control of susceptibility to colon cancer. Five different colon cancer susceptibility genes, Scc1-Scc5, have been described previously using the recombinant congenic strains. Two of these loci, Scc4...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
