Article
Mapping six new susceptibility to colon cancer (Scc) loci using a mouse interspecific backcross.
G3 (Bethesda, Md.) - 1 Dec 2012
Eversley Chevonne D, Yuying Xie, Pearsall R Scott, Threadgill David W
Abstract excerpt
Colorectal cancer (CRC) has a complex etiology resulting from the combination of multiple genetic and environmental factors, each with small effects. Interactions among susceptibility modifier loci make many of the loci difficult to detect in human genome-wide association studies. Previous analyses in mice have used classical inbred strains, which share large portions of their genomes due to common ancestry....
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