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Article

In vitro and in vivo characterization of a mouse adenovirus type 1 early region 3 null mutant.

Journal of virology - 1 Oct 1999

Cauthen A N, Brown C C, Spindler K R

Abstract excerpt

Previous attempts to construct a mouse adenovirus type 1 early region 3 (E3) null mutant by initiator codon mutagenesis were unsuccessful because one of the E3 proteins, gp11K, is synthesized as a fusion protein from a late viral mRNA (A. N. Cauthen and K. R. Spindler, Virology 259:119-128, 1999). Therefore, a different mutagenesis strategy was employed that inserted termination codons into all three reading...

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Identifiers

PMID: 10482617
DOI: 10.1128/JVI.73.10.8640-8646.1999
PMCID: PMC112884

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