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Article

Molecular characterization of a neuropathogenic and nonerythroleukemogenic variant of Friend murine leukemia virus PVC-211.

Journal of virology - 1 May 1992

Masuda M, Remington M P, Hoffman P M, Ruscetti S K

Abstract excerpt

PVC-211 murine leukemia virus (MuLV) is a replication-competent, ecotropic type C retrovirus that was isolated after passage of the Friend virus complex through F344 rats. Unlike viruses in the Friend virus complex, it does not cause erythroleukemia but causes a rapidly progressive hind limb paralysis when injected into newborn rats and mice. We have isolated an infectious DNA clone (clone 3d) of this virus which...

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Identifiers

PMID: 1560524
DOI: 10.1128/JVI.66.5.2798-2806.1992
PMCID: PMC241036

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