Article
Construction of mouse adenovirus type 1 mutants.
Methods in molecular medicine - 1 Jan 2007
Cauthen Angela N, Welton Amanda R, Spindler Katherine R
Abstract excerpt
Mouse adenovirus provides a model for studying adenovirus pathogenesis in the natural host. The ability to make viral mutants allows the investigation of specific mouse adenoviral gene contributions to virus-host interactions. Methods for propagation and titration of wild-type mouse adenovirus, production of viral DNA and viral DNA-protein complex, and transfection of mouse cells to obtain mouse adenovirus...
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