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Article

Phenotypes of major immediate-early gene mutants of mouse cytomegalovirus.

Medical microbiology and immunology - 1 Jun 2008

Busche Andreas, Angulo Ana, Kay-Jackson Penelope, Ghazal Peter, Messerle Martin

Abstract excerpt

Immediate-early (IE) genes are the first genes to be transcribed during the lytic replication cycle of cytomegaloviruses (CMV), and encode nonstructural proteins, which are assumed to have mainly regulatory functions. The IE proteins may play important roles in the pathogenesis of CMV in vivo, for instance during the establishment of latency and during reactivation. We constructed mouse CMV mutants with...

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PMID: 18239940
DOI: 10.1007/s00430-008-0076-3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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