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Article

ATM Is Upregulated During the Mitogenic Response in Peripheral Blood Mononuclear Cells

15 Sept 1999

Abstract excerpt

Patients with the human genetic disorder ataxia-telangiectasia (A-T) are characterized by immunodeficiency and a predisposition to develop lymphoid malignancies. The gene mutated in A-T patients, ATM, codes for a high molecular weight protein that is implicated in DNA damage recognition and cell cycle control. The ATM protein does not change in amount or cellular distribution throughout the cell cycle or in...

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Identifiers

PMID: 10477729
DOI: 10.1182/blood.v94.6.1998

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ATM Is Upregulated During the Mitogenic Response in Peripheral Blood Mononuclear CellsPMID 10477729Read ↗

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The p53-mediated DNA damage response to ionizing radiation in fibroblasts from ataxia-without-telangiectasia patients.Semantic proximity Read ↗

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ATM Activation and DNA Damage ResponseSemantic proximity Read ↗

Isolation of full-length ATM cDNA and correction of the ataxia-telangiectasia cellular phenotype.Semantic proximity Read ↗

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