Article
Ataxia telangiectasia mutated is essential during adult neurogenesis.
Genes & development - 1 Mar 2001
Allen D M, van Praag H, Ray J, Weaver Z, Winrow C J, Carter T A, Braquet R, Harrington E, Ried T, Brown K D, Gage F H, Barlow C
Abstract excerpt
Ataxia telangiectasia (A-T) is an autosomal recessive disease characterized by normal brain development followed by progressive neurodegeneration. The gene mutated in A-T (ATM) is a serine protein kinase implicated in cell cycle regulation and DNA repair. The role of ATM in the brain and the cons...
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