Article
neu mutation in schwannomas induced transplacentally in Syrian golden hamsters by N-nitrosoethylurea: high incidence but low allelic representation.
Journal of cancer research and clinical oncology - 1 Oct 1999
Buzard G S, Enomoto T, Hongyo T, Perantoni A O, Diwan B A, Devor D E, Reed C D, Dove L F, Rice J M
Abstract excerpt
Peripheral nerve tumors (PNT) and melanomas induced transplacentally on day 14 of gestation in Syrian golden hamsters by N-nitrosoethylurea were analyzed for activated oncogenes by the NIH 3T3 transfection assay, and for mutations in the neu oncogene by direct sequencing, allele-specific oligonucleotide hybridization, MnlI restriction-fragment-length polymorphism, single-strand conformation polymorphism, and...
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