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Article

Roles of the C terminus of Armadillo in Wingless signaling in Drosophila.

Genetics - 1 Sept 1999

Cox R T, Pai L M, Kirkpatrick C, Stein J, Peifer M

Abstract excerpt

Drosophila melanogaster Armadillo and its vertebrate homolog beta-catenin play multiple roles during development. Both are components of cell-cell adherens junctions and both transduce Wingless (Wg)/Wnt intercellular signals. The current model for Wingless signaling proposes that Armadillo binds the DNA-binding protein dTCF, forming a bipartite transcription factor that activates Wingless-responsive genes. In...

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Identifiers

PMID: 10471715
DOI: 10.1093/genetics/153.1.319
PMCID: PMC1460731

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Roles of the C terminus of Armadillo in Wingless signaling in Drosophila.PMID 10471715Read ↗

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