Article
A screen for mutations that suppress the phenotype of Drosophila armadillo, the beta-catenin homolog.
Genetics - 1 Aug 2000
Cox R T, McEwen D G, Myster D L, Duronio R J, Loureiro J, Peifer M
Abstract excerpt
During development signaling pathways coordinate cell fates and regulate the choice between cell survival or programmed cell death. The well-conserved Wingless/Wnt pathway is required for many developmental decisions in all animals. One transducer of the Wingless/Wnt signal is Armadillo/beta-catenin. Drosophila Armadillo not only transduces Wingless signal, but also acts in cell-cell adhesion via its role in the...
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