Article
Drosophila Wnt/Fz pathways.
Science's STKE : signal transduction knowledge environment - 10 May 2005
DasGupta Ramanuj, Boutros Michael, Perrimon Norbert
Abstract excerpt
Wnts [also known as Wingless (Wg)] are a family of conserved signaling molecules involved in a plethora of fundamental developmental and cell biological processes, such as cell proliferation, differentiation, and cell polarity. Dysregulation of the pathway can be detrimental, because several components are tumorigenic when mutated and are associated with hepatic, colorectal, breast, and skin cancers. First...
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