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Article

The segment polarity gene armadillo encodes a functionally modular protein that is the Drosophila homolog of human plakoglobin.

Cell - 21 Dec 1990

Peifer M, Wieschaus E

Abstract excerpt

The Drosophila segment polarity gene armadillo is required for pattern formation within embryonic segments and imaginal discs. We have found that armadillo is highly conserved during evolution; it is 63% identical to human plakoglobin, a protein found in adhesive junctions joining epithelial and other cells. We have examined arm protein localization in a number of larval tissues and found that arm protein...

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PMID: 2261639
DOI: 10.1016/0092-8674(90)90413-9

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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The segment polarity gene armadillo encodes a functionally modular protein that is the Drosophila homolog of human plakoglobin.PMID 2261639Read ↗

The armadillo family of structural proteins.Semantic proximity Read ↗

Spatial expression of the Drosophila segment polarity gene armadillo is posttranscriptionally regulated by wingless.Semantic proximity Read ↗

An in vivo structure-function study of armadillo, the beta-catenin homologue, reveals both separate and overlapping regions of the protein required for cell adhesion and for wingless signaling.Semantic proximity Read ↗

The segment polarity gene armadillo interacts with the wingless signaling pathway in both embryonic and adult pattern formation.Semantic proximity Read ↗

A screen for identifying genes interacting with armadillo, the Drosophila homolog of beta-catenin.Semantic proximity Read ↗

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Targeted mutation of plakoglobin in mice reveals essential functions of desmosomes in the embryonic heart.Semantic proximity Read ↗

A screen for mutations that suppress the phenotype of Drosophila armadillo, the beta-catenin homolog.Semantic proximity Read ↗

Embryonic heart and skin defects in mice lacking plakoglobin.Semantic proximity Read ↗

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Roles of the C terminus of Armadillo in Wingless signaling in Drosophila.Semantic proximity Read ↗

Expression of the Armadillo family member p120cas1B in Xenopus embryos affects head differentiation but not axis formation.Semantic proximity Read ↗

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