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Article

DNA binding site selection by RNA polymerase II TAFs: a TAF(II)250-TAF(II)150 complex recognizes the initiator.

The EMBO journal - 1 Sept 1999

Chalkley G E, Verrijzer C P

Abstract excerpt

Basal transcription factor TFIID comprises the TATA-box-binding protein, TBP, and associated factors, the TAF(II)s. Previous studies have implicated TAF(II)250 and TAF(II)150 in core promoter selectivity of RNA polymerase II. Here, we have used a random DNA binding site selection procedure to identify target sequences for these TAFs. Individually, neither TAF(II)250 nor TAF(II)150 singles out a clearly...

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Share to Histone Acetyltransferases
Share to Recombinant Proteins
Share to RNA Polymerase II

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Sequence Homology, Nucleic Acid

Share to TATA-Binding Protein Associated Factors

Share to Transcription Factor TFIID

Share to Transcription Factors, TFII

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Source

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Identifiers

PMID: 10469661
DOI: 10.1093/emboj/18.17.4835
PMCID: PMC1171555

Genes

TBP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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