Article
Human TAFII250 interacts with RAP74: implications for RNA polymerase II initiation.
Genes & development - 15 Nov 1995
Ruppert S, Tjian R
Abstract excerpt
Accurate and regulated transcription by RNA polymerase II requires the assembly of an initiation complex involving multiple protein-DNA and protein-protein interactions. A key event is binding of TFIID, a complex consisting of TBP and associated factors (TAFs) to the template DNA. The TAF subunits of TFIID carry out diverse functions critical for transcription, including specific contact with enhancer proteins...
Topics
- Amino Acids
- Base Sequence
- Binding Sites
- Carrier Proteins
- DNA-Binding Proteins
- HeLa Cells
- Histone Acetyltransferases
- Humans
- Molecular Sequence Data
- Mutation
- Nuclear Proteins
- Oligonucleotides