Article
Direct recognition of initiator elements by a component of the transcription factor IID complex.
Genes & development - 1 Apr 1994
Kaufmann J, Smale S T
Abstract excerpt
A core promoter element called an initiator (Inr) overlaps the transcription start site of numerous mammalian protein-coding genes. In promoters that lack a TATA box, the Inr is functionally analogous to TATA, in that it is capable of directing basal transcription by RNA polymerase II and of dete...
Topics
- Animals
- Base Sequence
- Binding Sites
- DNA
- DNA Nucleotidylexotransferase
- Humans
- Molecular Sequence Data
- Mutation
- Promoter Regions, Genetic
- Sp1 Transcription Factor
- TATA Box
- Transcription Factor TFIID
- Transcription Factors
- Transcription, Genetic
