Article
Analysis of apolipoprotein E, alpha1-antichymotrypsin and presenilin-1 genes polymorphisms in dementia caused by normal pressure hydrocephalus in man.
Neuroscience letters - 4 Jul 1997
Nacmias B, Tedde A, Guarnieri B M, Petruzzi C, Ortenzi L, Serio A, Amaducci L, Sorbi S
Abstract excerpt
Normal pressure hydrocephalus (NPH) is characterized by dementia, gait disorders and urinary incontinence. Apolipoprotein E (ApoE) epsilon4 allele has been associated with severity of dementia in Alzheimer's disease (AD) and in other forms of dementia. Moreover, homozygosity of the A allele of th...
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