Article
Polymorphisms of CYP2C19 and CYP2D6 in Israeli ethnic groups.
American journal of pharmacogenomics : genomics-related research in drug development and clinical practice - 1 Jan 2004
Luo Huai-Rong, Aloumanis Vasileios, Lin Keh-Ming, Gurwitz David, Wan Yu-Jui Yvonne
Abstract excerpt
BACKGROUND: The cytochrome P450 isoenzymes CYP2C19 and CYP2D6 catalyze reactions involved in the metabolism of many widely used drugs. Their polymorphisms give rise to important interindividual and interethnic variability in the metabolism and disposition of several therapeutic agents and may cau...
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