Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Lymph node metastasis is associated with allelic loss on chromosome 13q12-13 in esophageal squamous cell carcinoma.

Cancer research - 1 Aug 1999

Harada H, Tanaka H, Shimada Y, Shinoda M, Imamura M, Ishizaki K

Abstract excerpt

Allelotype analysis of whole chromosomes showed that loss of heterozygosity (LOH) on 13q was exclusively associated with lymph node metastasis and poor prognosis in esophageal squamous cell carcinoma (ESC). To identify a locus responsible for lymph node metastasis, we performed fine deletion mapping on 13q by analyzing 60 ESCs with 18 polymorphic markers. Allelic loss was observed with at least one marker in 34...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to BRCA2 Protein
Share to Carcinoma, Squamous Cell
Share to Chromosomes, Human, Pair 13

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Esophageal Neoplasms

Share to Genes, Retinoblastoma

Share to Genes, Tumor Suppressor

Share to Loss of Heterozygosity

Share to Lymphatic Metastasis

Source

Identifiers

PMID: 10446988

Genes

BRCA2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Lymph node metastasis is associated with allelic loss on chromosome 13q12-13 in esophageal squamous cell carcinoma.PMID 10446988Read ↗

Polymorphism and allelic loss at the AS3 locus on 13q12-13 in esophageal squamous cell carcinoma.Semantic proximity Read ↗

Allelotyping of esophageal squamous-cell carcinoma on chromosome 13 defines deletions related to family history.Semantic proximity Read ↗

Evidence for a familial esophageal cancer susceptibility gene on chromosome 13.Semantic proximity Read ↗

Allelic loss on chromosome 13q14 and mutation in deleted in cancer 1 gene in esophageal squamous cell carcinoma.Semantic proximity Read ↗

Clinicopathological significance of loss of heterozygosity on chromosome 13q in hepatocellular carcinoma.Semantic proximity Read ↗

Identification of distinct regions of allelic loss on chromosome 13q in nasopharyngeal cancer from paraffin embedded tissues.Semantic proximity Read ↗

Correlation of allelic losses and clinicopathological factors in 504 primary breast cancers.Semantic proximity Read ↗

Three distinct regions of allelic loss at 13q14, 13q21-22, and 13q33 in prostate cancerSemantic proximity Read ↗

Allelotype analysis of esophageal squamous cell carcinoma.Semantic proximity Read ↗

Multiple regions of deletion on chromosome arm 13q in head-and-neck squamous-cell carcinoma.Semantic proximity Read ↗

Allelic loss in esophageal squamous cell carcinoma patients with and without family history of upper gastrointestinal tract cancer.Semantic proximity Read ↗

Allelotype of head and neck squamous cell carcinoma.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.