Article
Allelic loss on chromosome 13q14 and mutation in deleted in cancer 1 gene in esophageal squamous cell carcinoma.
Oncogene - 16 Jan 2003
Li Wen-Jun, Hu Nan, Su Hua, Wang Chaoyu, Goldstein Alisa M, Wang Yuan, Emmert-Buck Michael R, Roth Mark J, Guo Wen-Jie, Taylor Philip R
Abstract excerpt
Previous studies have shown frequent allelic loss on chromosome 13 in esophageal squamous cell carcinoma (ESCC). We assessed the frequency of allelic loss on chromosome 13q14 and mutations of deleted in cancer 1 (DICE1) (also found on 13q14) in ESCC patients to determine if this candidate tumor suppressor gene has a role in the development of ESCC, and whether this gene was an inactivation target for allelic loss...
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