Article
Allelic loss in esophageal squamous cell carcinoma patients with and without family history of upper gastrointestinal tract cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research - 1 Nov 1999
Hu N, Roth M J, Emmert-Buck M R, Tang Z Z, Polymeropolous M, Wang Q H, Goldstein A M, Han X Y, Dawsey S M, Ding T, Giffen C, Taylor P R
Abstract excerpt
Chromosomal regions with frequent allelic loss may point to major susceptibility genes that will assist in understanding molecular events involved in esophageal carcinogenesis. Esophageal squamous cell carcinoma samples and blood from 46 patients, including 23 patients with and 23 patients without a family history of upper gastrointestinal cancer, were screened using laser microdissected DNA and tested for loss...
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