Article
Multiple regions of deletion on chromosome arm 13q in head-and-neck squamous-cell carcinoma.
International journal of cancer - 22 Oct 1999
Gupta V K, Schmidt A P, Pashia M E, Sunwoo J B, Scholnick S B
Abstract excerpt
Several lines of evidence suggest that the progression of head-and-neck squamous-cell carcinoma (HNSCC) involves inactivation of at least one and possibly several tumor-suppressor genes on the long arm of chromosome 13. The fact that neither Rb1 nor BRCA2 appears to be inactivated in the majority of head-and-neck cancers suggests that novel tumor-suppressor genes are involved. We have used microsatellite repeat...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
