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Article

Interaction of cystatin C variants with papain and human cathepsins B, H and L.

Journal of enzyme inhibition - 1 Jan 1999

Cimerman N, Prebanda M T, Turk B, Popovic T, Dolenc I, Turk V

Abstract excerpt

Recombinant human cystatin C and two of its mutants were expressed in Escherichia coli. The recombinant inhibitor was found to be identical to authentic cystatin C as judged by isoelectric focusing (pI 9.2) and kinetics of inhibition of papain and human cathepsins B, H and L. N-terminal truncation of 8 residues resulted in a decrease of isoelectric point (pI 7.8), but the inhibitory properties were similar to...

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Identifiers

PMID: 10445041
DOI: 10.3109/14756369909036552

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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