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Article

Mutation in the beta 2m gene is not a frequent event in head and neck squamous cell carcinomas.

Human immunology - 1 Aug 1999

Feenstra M, Rozemuller E, Duran K, Stuy I, van den Tweel J, Slootweg P, de Weger R, Tilanus M

Abstract excerpt

In cryostat sections of 84 head and neck squamous cell carcinomas (HNSCC) HLA class I and beta 2m expression was analysed using monomorphic and locus specific monoclonal antibodies. Loss of expression was heterogeneous and none of the tumours tested showed a total loss of HLA class I and/or beta 2m when analysed with W6/32, which recognises HLA class I determinants and anti-beta 2m MoAbs. Weak HLA class I and...

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Share to Antibodies, Monoclonal
Share to ATP Binding Cassette Transporter, Subfamily B, Member 2

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Share to Carcinoma, Squamous Cell

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Source

Identifiers

PMID: 10439315
DOI: 10.1016/s0198-8859(99)00015-4

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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