Article
HLA class I antigen down-regulation in primary ovary carcinoma lesions: association with disease stage.
Clinical cancer research : an official journal of the American Association for Cancer Research - 1 Jan 2005
Vitale Marco, Pelusi Giuseppe, Taroni Beatrice, Gobbi Giuliana, Micheloni Cristina, Rezzani Rita, Donato Francesco, Wang Xinhui, Ferrone Soldano
Abstract excerpt
PURPOSE: To investigate TAP1, TAP2, and HLA class I antigen expression in primary ovarian carcinoma lesions and to assess the clinical significance of defects in the expression of these molecules. EXPERIMENTAL DESIGN: Fifty-one formalin-fixed, paraffin-embedded primary ovarian carcinoma lesions were stained with affinity-purified rabbit anti-TAP1 and anti-TAP2 antibodies and with anti-HLA class I heavy chain...
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