Article
High frequency of HLA-B44 allelic losses in human solid tumors.
Human immunology - 1 Oct 2003
Cabrera Teresa, Maleno Isabel, Lopez-Nevot Miguel Angel, Redondo Maximino, Fernandez Maria Angustias, Collado Antonia, Garrido Federico
Abstract excerpt
Human leukocyte antigen (HLA) class I downregulation, a frequent phenomenon observed in a variety of human tumors, favors tumor immune escape from T-lymphocyte recognition. However, it is not known whether a particular HLA class I allele is lost more frequently than others. To address this question we analyzed HLA class I expression in tumor tissues derived from 300 patients diagnosed as having breast,...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
