Article
Complex inheritance and localizing disease genes.
Human heredity - 1 Jan 2000
Hoh J J, Ott J
Abstract excerpt
Most methods for localizing genes underlying complex traits work under the implicit or explicit assumption of a single disease gene with the possible exception of heterogeneity, that is, different disease genes in different families. We discuss current single-locus and multi-locus methods. Novel approaches are proposed that take into account all marker loci over the genome. A simple example is given for an...
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