Article
ERV-3 envelope expression and congenital heart block: what does a physiological knockout teach us.
Autoimmunity - 1 Jan 1999
de Parseval N, Forrest G, Venables P J, Heidmann T
Abstract excerpt
Congenital heart block is a serious condition with significant mortality due in most cases to the transplacental transfer of autoantibodies from an otherwise asymptomatic mother. Although SSA/Ro and SSB/La autoantibodies have been implicated, attention has focused recently on autoantibodies to envelope proteins of endogenous retrovirus-3 (ERV-3). We have recently identified in 1% of the caucasian population a...
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