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Article

Cardiac expression of 52β, an alternative transcript of the congenital heart block‐associated 52‐kd SS‐A/Ro autoantigen, is maximal during fetal development

1 Apr 1997

Abstract excerpt

OBJECTIVE: Congenital heart block (CHB), associated with antibodies to SS-A/Ro and SS-B/La, is most often detected between 18 and 24 weeks of gestation, yet the maternal heart is unaffected. We recently described an alternatively spliced 52-kd SS-A/Ro messenger RNA (mRNA) derived from the skipping of exon 4 which encodes a smaller protein, 52beta (MW 45 kd), recognized by CHB maternal antisera. This study was...

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Identifiers

PMID: 9125247
DOI: 10.1002/art.1780400410

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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