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Article

Complete congenital heart block is associated with increased autoantibody titers against calreticulin

1 Mar 1996

Abstract excerpt

Complete congenital heart block (CCHB) is associated with anti-Ro/SS-A and anti-La/SS-B antibodies. Calreticulin, a calcium-binding, multi-functional protein of the endoplasmic reticulum with C-terminal KDEL-sequence, is not part of the Ro/SS-A ribonucleoprotein complex. In this study anti-calreticulin autoantibody responses in serum samples from 18 infants with CCHB, their mothers and in a control group of 11...

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Identifiers

PMID: 8904349
DOI: 10.1046/j.1365-2362.1996.120270.x

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