Article
Role of HLA in congenital heart block: susceptibility alleles in children.
Lupus - 1 Jan 1999
Sirén M K, Julkunen H, Kaaja R, Ekblad H, Koskimies S
Abstract excerpt
Congenital heart block (CHB) is a syndrome of uncertain pathogenesis leading to cardiac conduction disturbances in the foetus and newborns. It has been proposed that maternal antibodies transmit immunological injury in the developing foetal heart, thus causing irreversible damage of the atrioventricular node, leading to third-degree atrioventricular block. However, some genetic or environmental factors may also...
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