Risk of smoking for squamous and small cell carcinomas of the lung modulated by combinations of CYP1A1 and GSTM1 gene polymorphisms in a Japanese population.

doi:10.1093/carcin/16.10.2331

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Article

Risk of smoking for squamous and small cell carcinomas of the lung modulated by combinations of CYP1A1 and GSTM1 gene polymorphisms in a Japanese population.

Carcinogenesis - 1 Oct 1995

Kihara M, Kihara M, Noda K

Abstract excerpt

Genes for cytochrome P4501A1 (CYP1A1) and glutathione S-transferase class mu (GSTM1) have been shown to be polymorphic, and have been implicated in tobacco-related carcinogenesis. In the present study, the role of the combined genotypes CYP1A1 and GSTM1 as a possible modulator of smoking related...

Topics

Aged
Alleles
Carcinoma, Small Cell
Carcinoma, Squamous Cell
Cytochrome P-450 Enzyme System
Deoxyribonuclease HpaII
Female
Gene Deletion
Gene Frequency
Genotype
Glutathione Transferase
Homozygote

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Humans

Isoenzymes

Japan

Lung Neoplasms

Male

Middle Aged

Source

Open in PubMed

Identifiers

PMID: 7586131
DOI: 10.1093/carcin/16.10.2331

Genes

GSTM1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-7586131-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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