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Article

Genetic polymorphisms of tobacco- and alcohol-related metabolizing enzymes and oral cavity cancer.

International journal of cancer - 26 Nov 1999

Katoh T, Kaneko S, Kohshi K, Munaka M, Kitagawa K, Kunugita N, Ikemura K, Kawamoto T

Abstract excerpt

Both genetic and environmental factors are involved in the development of cancer. Oral cavity cancer has been reported to be epidemiologically associated with tobacco and alcohol consumption. We examined genetic polymorphisms of the glutathione-S-transferase (GST) M1/T1, cytochrome P-450 (CYP) 1A1/2E1 and aldehyde dehydrogenase 2 (ALDH2) genes in 92 Japanese patients with oral cavity cancer and 147 unrelated...

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Source

Identifiers

PMID: 10521794
DOI: 10.1002/(sici)1097-0215(19991126)83:5<606::aid-ijc6>3.0.co;2-p

Genes

ALDH2
GSTM1
GSTT1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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