Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

11q13 allelic imbalance discriminates pulmonary carcinoids from tumorlets. A microdissection-based genotyping approach useful in clinical practice.

The American journal of pathology - 1 Aug 1999

Finkelstein S D, Hasegawa T, Colby T, Yousem S A

Abstract excerpt

Pulmonary tumorlets are minute neuroendocrine cell proliferations believed to be precursor lesions to pulmonary carcinoids. Little is known of their molecular pathogenesis because of their small size. Using tissue microdissection, we evaluated 11q13 region allelic imbalance in the pathogenesis of pulmonary tumorlet/carcinoid lesions. The int-2 gene was selected because of its chromosomal location at 11q13 in...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Carcinoid Tumor
Share to Chromosomes, Human, Pair 11

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Dissection

Share to Fibroblast Growth Factor 3

Share to Fibroblast Growth Factors

Share to Ligases

Share to Von Hippel-Lindau Tumor Suppressor Protein

Share to WT1 Proteins

Source

Open in PubMed Open full text

Identifiers

PMID: 10433956
DOI: 10.1016/S0002-9440(10)65159-0
PMCID: PMC1866849

Genes

MEN1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

11q13 allelic imbalance discriminates pulmonary carcinoids from tumorlets. A microdissection-based genotyping approach useful in clinical practice.PMID 10433956Read ↗

Loss of heterozygosity on chromosome arm 11q in lung carcinoids.Semantic proximity Read ↗

Allelic deletions on chromosome 11q13 in multiple tumors from individual MEN1 patients.Semantic proximity Read ↗

Deletions of 11q22.3-q25 Are Associated with Atypical Lung Carcinoids and Poor Clinical OutcomeSemantic proximity Read ↗

Carcinoid tumors frequently display genetic abnormalities involving chromosome 11.Semantic proximity Read ↗

Association of genetic defects in primary resected lung adenocarcinoma revealed by targeted allelic imbalance analysis.Semantic proximity Read ↗

Allelic alterations in well-differentiated neuroendocrine tumors (carcinoid tumors) identified by genome-wide single nucleotide polymorphism analysis and comparison with pancreatic endocrine tumors.Semantic proximity Read ↗

High resolution chromosome 3p allelotyping of human lung cancer and preneoplastic/preinvasive bronchial epithelium reveals multiple, discontinuous sites of 3p allele loss and three regions of frequent breakpoints.Semantic proximity Read ↗

Molecular Evidence for Independent Origin of Multifocal Neuroendocrine Tumors of the Enteropancreatic AxisSemantic proximity Read ↗

Genetic events in tumour initiation and progression in multiple endocrine neoplasia type 2.Semantic proximity Read ↗

Identification of MEN1 gene mutations in sporadic carcinoid tumors of the lungSemantic proximity Read ↗

Microsatellite instability and allelic losses in neuroendocrine tumors of the gastro-entero-pancreatic system.Semantic proximity Read ↗

Allelotyping analysis suggesting a consecutive progression from intratubular germ cell neoplasia to seminoma and then to embryonal carcinoma of the adult testis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.