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Article

Carcinoid tumors frequently display genetic abnormalities involving chromosome 11.

The Journal of clinical endocrinology and metabolism - 1 Sept 1996

Jakobovitz O, Nass D, DeMarco L, Barbosa A J, Simoni F B, Rechavi G, Friedman E

Abstract excerpt

Carcinoid tumors are neuroendocrine neoplasms that are encountered either sporadically or as part of a familial syndrome, most notably-multiple endocrine neoplasia type 1 (MEN1). The MEN1 gene localizes to chromosome 11 (11q13) and presumably functions as a tumor suppressor gene. The molecular mechanisms underlying carcinoid tumor development and their clonal composition remain largely unknown. To establish...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 8784062
DOI: 10.1210/jcem.81.9.8784062

Genes

MEN1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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Carcinoid tumors frequently display genetic abnormalities involving chromosome 11.PMID 8784062Read ↗

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Deletion of chromosome 1, but not mutation of MEN-1, predicts prognosis in sporadic pancreatic endocrine tumors.Semantic proximity Read ↗

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Allelic deletions on chromosome 11q13 in multiple tumors from individual MEN1 patients.Semantic proximity Read ↗

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